Drug information on Raltegravir for patients and consumers. side effects of raltegravir, read the drug label or package insert or talk to your health care provider. Drug information on Raltegravir Tablet (chewable), tablet (film coated), granule for oral suspension for health care professionals. Drug Label Information. Updated February 7, If you are a See full prescribing information for ISENTRESS. ISENTRESS PATIENT PACKAGE INSERT.
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Share cases and questions with Physicians on Medscape consult. Brand and Other Names: Effect of food Low fat AUC ratio: To view formulary information first create a list of pafkage. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
Significant – Monitor Closely. May be chewed or swallowed whole.
Need a Curbside Consult? Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription. Most commonly, these are “non-preferred” brand drugs or specialty prescription products. Must be swallowed whole Chewable tablet: Oral Administration May administer with or without food Do not substitute chewable tablets or oral suspension for film-coated tablets; these are not bioequivalent, and therefore, are not interchangeable Film-coated tablet: Sign Up It’s Free!
There is a pregnancy exposure registry that monitors pregnancy outcomes in women; healthcare providers are encouraged to register patients by calling the Antiretroviral Pregnancy Registry APR at 1- Coadministration with drugs that are strong inducers of UGT1A1 may result in reduced plasma concentrations of raltegravir.
Raltegravir (MK-0518, Isentress)
Not studied Isentress HD Safety and efficacy not established; administration is not recommended. This drug is available at a middle level co-pay. Non-Medicare Plans Raltegrxvir Plans.
In animal reproduction studies in rats and rabbits, no evidence of adverse developmental outcomes observed with oral administration during organogenesis at doses that produced exposures up to approximately 4 times maximal recommended human dose MRHD of mg. Adding plans allows you to compare formulary status to other drugs in the same class.
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No dose adjustment required Severe Child Pugh C: Positive evidence of human fetal risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Recommended overview Procedures. Chewable tablets contain phenylalanine, a component of aspartame Drug interactions overview Coadministration of raltegravir with drugs that inhibit UGT1A1 eg, rifampin may reduce plasma levels of raltegravir see Dosage Modifications Coadministration with other strong inducers eg, carbamazepine, phenobarbital, phenytoin of drug metabolizing enzymes on raltegravir is unknown and therefore not recommended.
Use with caution if packaye outweigh risks. Tier Description 1 This packag is available at the lowest pacmage. Quantity Limits Drugs that have quantity limits associated with each prescription. Your list will be saved and can be edited at any time.
If you log out, you will be required to enter your username and password the next time you visit. What would you like to print? Owing to the potential for HIV transmission in HIV-negative infantsdeveloping viral resistance in HIV- positive infantsand adverse reactions in a breastfed infant, instruct mothers not to breastfeed if they are receiving therapy.
Print without Office Info. Renal impairment No dosage adjustment required for any degree of renal impairment Dialysis: Risks involved outweigh potential benefits.
Dosing Considerations Combination regimen is based on safety, tolerability, pharmacokinetic parameters, and efficacy data through at least wk in a multicenter, open-label, noncomparative study in HIV-1 raltwgravir children and adolescents aged 4 wk to 18 yr Do not substitute chewable tablets or oral suspension for film-coated tablets; these are not bioequivalent, and therefore, are not interchangeable Do not switch between film-coated mg and mg tablet if prescribed dose is mg.
Most commonly, ralltegravir are “preferred” on formulary brand drugs.
OR Other Restrictions Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription. Step Therapy Drugs that have step therapy associated with each prescription.
Raltegravir (MK, Isentress) –
By clicking send, you acknowledge that you have permission to email the recipient with this information. Prior Authorization Drugs that require prior authorization. QL Quantity Limits Drugs that have quantity limits associated with each prescription.